| 产品详情 |
Thymosin Beta 4 is a naturally occurring peptide encoded by the TMSB4X gene located on Chr. X in humans. It is found in high concentrations in blood platelets, wound fluid and other tissues in the body. Tβ-4 is a major actin regulating peptide and the primary function is to stimulate the productions of T cells, which plays important part of the immune system. The thymosin beta-4 peptide, if used after a heart attack, might reactivate cardiac progenitor cells to repair damaged heart tissue. Recombinant Human Tβ-4 is a 4.9kDa protein containing 44 amino acid residues.
Product Information
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Product Name
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Recombinant Human Thymosin beta 4
(rHuTβ-4)
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Cat. No.
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GH052
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Synonyms
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Fx
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Molecular weight
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Approximately 4.9kDa, a single non-glycosylated polypeptide chain containing 44 amino acids.
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accession
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P62328 Ser2-Ser44
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AA sequence
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SDKPDMAEIEKFDKSKLKKTETQEKNPLPSKETIEQEKQAGES
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Purity
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＞97% by SDS-PAGE or HPLC
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Formulation
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Lyophilized from a 0.2mm filtered solution in PBS, pH 7.2.
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Biological activity
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Fully biologically active when compared to standard. The biological activity determined by its ability to produce a protective effect against hydrogen peroxide in primary lung fibroblasts is in a concentration range of 0.5-10μg/ml.
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Endotoxin level
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Less than 0.1EU/mg of rHuTβ-4 as determined by LAL method
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Reconstitution
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Before use this product, please read the direction below carefully.
1、 This vial must be briefly centrifuged prior to opening to bring the contents to the bottom.
2、 Reconstitute in sterile distilled water or aqueous buffer containing 0.1% BSA to a concentration of 0.1-1.0mg/ml.
Stock solutions should be apportioned into working aliquots and stored at ≤-20℃. Further dilutions should be made in appropriate buffered solutions.
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Storage/ Stability
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For long term storage, the product should be stored≤-20℃.
36 months, -20 to -70℃ as supplied.
1 month, 2 to 8℃ under sterile conditions after reconstitution;
3 months, -20 to -70℃ under sterile conditions after reconstitution.
Please avoid repeated freeze-thaw cycles.
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THIS PRODUCT IS FOR RESEARCH, LABORATORY AND EVALUATION PURPOSE ONLY.
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