| 产品详情 |
PTHrP, also named parathyroid hormone-related protein, is belonging to the parathyroid hormone family. PTHrP is expressed in cancer cells (breast cancer, certain types of lung cancer including squamous cell lung carcinoma). The receptor for PTHrP is PTHR1. PTHrP plays a central role in regulating the hypercalcemia. PTHrP shares 86% a.a. identity with murine PTHLH. Recombinant human PTHrP is a 9.9kDa protein consisting of 86 amino acids.
u Product Information
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Product Name
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Recombinant Human Parathyroid Hormone-related protein
(rHuPTHrP)
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Synonyms
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Parathyroid Hormone-related Protein
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Source
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Expressed in E. coli.
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Molecular weight
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Approximately 9.9kDa, a single polypeptide chain containing 86 amino acids.
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Accession
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P12272 Ala37-Pro122
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AA Sequence
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AVSEHQLLHDKGKSIQDLRRRFFLHHLIAEIHTAEIRATSEVSPNSKPSPNTKNHPVRFGSDDEGRYLTQETNKVETYKEQPLKTP
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Purity
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＞98% by SDS-PAGE or HPLC.
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Biological activity
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Not available
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Formulation
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Lyophilized from a 0.2µm filtered concentrated solution in 20mM PB, pH6.0,300 mM NaCl.
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Endotoxin level
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＜0.01EU/μg rHuPTHrP protein as determined by LAL method.
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Reconstitution
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Before use this product, please read the direction below carefully.
1、 This vial must be briefly centrifuged prior to opening to bring the contents to the bottom.
2、 Reconstitute in sterile distilled water or aqueous buffer containing 0.1%BSA to a concentration of 0.1-1.0mg/ml.
Stock solutions should be apportioned into working aliquots and stored at ≤-20℃. Further dilutions should be made in appropriate buffered solutions.
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Storage/ Stability
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For long term storage, the product should be stored ≤-20℃.
36 months, -20 to -70℃ as supplied.
1 month, 2 to 8℃ under sterile conditions after reconstitution;
3 months, -20 to -70℃ under sterile conditions after reconstitution.
Please avoid repeated freeze-thaw cycles.
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THIS PRODUCT IS FOR RESEARCH, LABORATORY AND EVALUATION PURPOSE ONLY.
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